Motor Unit Number Estimation In Idiopathic Parkinson's Disease

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Motor unit number estimates in idiopathic Parkinson's disease.

We previously reported changes in motor unit morphology in patients with Parkinson's disease (PD) using subjective and computerized quantitative electromyography. Now, we present data on motor unit number estimates (MUNE) to address the hypothesis of motor neuron dropout in PD. Twenty patients with PD and 20 age-matched control subjects were screened by clinical criteria and nerve conduction st...

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Motor Unit Number Estimation in Normal and Parkinsonism Model of Medial Gastrocnemius Muscle in Rats

    Motor units (MUs) reflect the function of the central nervous motor system. Thus, the estimated MU number is a good option to investigate the functional movement disorder in the Parkinson’s disease (PD). The purpose of this study was to compare the estimated MUs number in the medial gastrocnemius (MG) muscle of the normal rats and those with the Parkinsonism. The MG muscle of two age-matche...

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Simulations of motor unit number estimation techniques.

Motor unit number estimation (MUNE) is an electrodiagnostic procedure used to evaluate the number of motor axons connected to a muscle. All MUNE techniques rely on assumptions that must be fulfilled to produce a valid estimate. As there is no gold standard to compare the MUNE techniques against, we have developed a model of the relevant neuromuscular physiology and have used this model to simul...

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Motor unit number estimation--a Bayesian approach.

All muscle contractions are dependent on the functioning of motor units. In diseases such as amyotrophic lateral sclerosis (ALS), progressive loss of motor units leads to gradual paralysis. A major difficulty in the search for a treatment for these diseases has been the lack of a reliable measure of disease progression. One possible measure would be an estimate of the number of surviving motor ...

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Motor Unit Number Estimation and Motor Unit Action Potential Analysis in Carpal Tunnel Syndrome

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ژورنال

عنوان ژورنال: Dusunen Adam: The Journal of Psychiatry and Neurological Sciences

سال: 2011

ISSN: 1018-8681,1309-5749

DOI: 10.5350/dajpn2011240202t